|
IBM Interim Genetic Maps
Map Construction Linkage groups were constructed using MapMaker for UNIX version 3.0 (Whitehead Institute, Cambridge, MA). Initially groups were defined at LOD 6.0, 50 cM. Subsequently some chromosomes were regrouped at lower LODs. The maps were constructed using the RI self and Haldane options. The "order" command was used to construct initial frameworks containing a subset of markers mapped at MU. Once refined, these orders were frameworked. The remaining loci were assigned to linkage groups at LOD 4.0 and frameworked using the MU framework as a starting point. New frameworks containing these markers were set after markers which significantly inflated the map were discarded. All remaining markers were assigned at LOD 4.0 then placed against the framework. Framework map orders were evaluated and adjusted using the output from the "ripple" command (5 loci, LOD 3.0). Please forward any questions or comments to:
|
